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Heat oven to 350ºF.
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Melt butter in a small skillet over medium-high heat. Add onion and garlic; cook 5 minutes, stirring occasionally. Remove from heat and let cool.
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In a large bowl add ground turkey, quick oats, egg, 1/4 cup ketchup, Worcestershire sauce, and pepper.
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Add cooled onions and garlic. Mix together well.
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Press into regular sized loaf pan or three small loaf pans.
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Spread some extra ketchup over top.
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Bake 30-45 minutes or until the internal temperature of meatloaf is 165ºF.
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Let cool for 5 minutes before serving.